Valproate may be more effective than lithium for treating mania, rapid cycling bipolar disorder, or mixed states. It does not seem to be as effective as lithium for the treatment of depressive states, however.
The most worrisome side effects of sodium valproate bipolar medication treatment are liver damage and decreased platelets.
https://www.mentalhelp.net/articles/bipolar-disorder-treatment-valproate-and-carbamazepine/
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