...Inducing a ketogenic state in patients with cancer may be a useful adjunct (附屬的) to cancer treatment by affecting tumor glucose metabolism and growth while maintaining the patient's nutritional status. A ketogenic diet consisting of 60% medium-chain triglyceride (MCT) oil, 20% protein, 10% carbohydrate, and 10% other dietary fats was provided to a select group of pediatric patients with advanced-stage cancer to test the effects of dietary-induced ketosis on tumor glucose metabolism. Issues of tolerance and compliance for patients consuming an oral diet (consisting of normal table foods and daily MCT oil “shakes”) and for patients receiving an enteral formula (by nasogastric tube or gastrostomy feeding) are reviewed. Preliminary (初步的) use of the MCT oil-based diet suggests a potential in pediatric patients with cancer.
Nebeling, L. C. (1995) Implementing A Ketogenic Diet Based on Medium-chain Triglyceride Oil in Pediatric Patients with Cancer. Journal of the American Dietetic Association, 95(6), 693-697.
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