Peripheral nerve injury (PNI) is a very common chronic trauma seen in clinics and is characterized by permanent sensory impairment and severe motor dysfunction...Although peripheral nerve fibers show considerable potential for self-regeneration, the outcome is generally unsatisfactory, resulting in weak motor recovery and irreversible sensory dysfunction.
Li, R., & Li, D. H. (2020). Growth factors-based therapeutic strategies and their underlying signaling mechanisms for peripheral nerve regeneration. Acta Pharmacologica Sinica, 41, 1289–1300. https://www.nature.com/articles/s41401-019-0338-1
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