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2019年12月17日星期二

Prebiotics

Prebiotics are a group of nutrients that are degraded by gut microbiota. Their relationship with human overall health has been an area of increasing interest in recent years. They can feed the intestinal microbiota, and their degradation products are short-chain fatty acids that are released into blood circulation, consequently, affecting not only the gastrointestinal tracts but also other distant organs.

Various types of microorganisms, known as gut microbiota, are inhabitants of the human gastrointestinal tract. It has been reported that there are 1010–1012 live microorganisms per gram in the human colon. The resident microbial groups in the stomach, small, and large intestine are crucial for human health. The majority of these microorganisms, which are mostly anaerobes, live in the large intestine.

Human diet is the chief source of energy for their growth. Particularly, non-digestible carbohydrates can highly modify the composition and function of gut microbiota. Beneficial intestinal microbes ferment these non-digestible dietary substances called prebiotics and obtain their survival energy from degrading indigestible binds of prebiotics. As a result of this, prebiotics can selectively influence gut microbiota. On the other hand, the gut microbiota affects intestinal functions, such as metabolism and integrity of the intestine. Moreover, they can suppress pathogens in healthy individuals.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463098/

Prebiotics are a type of fiber that the human body cannot digest. They serve as food for probiotics, which are tiny living microorganisms, including bacteria and yeast. Both prebiotics and probiotics may support helpful bacteria and other organisms in the gut.

https://www.medicalnewstoday.com/articles/323490.php

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