剖腹產、順產、微生物群與免疫疾病

最近的流行病學研究證據表明，選擇性剖腹產與新生兒異常的短期免疫有關，並且增加患哮喘、過敏、1 型糖尿病和乳糜瀉等免疫疾病的風險。

Recent epidemiological studies provide evidence that elective cesarean section is associated with aberrant short-term immune responses in the newborn infant, and a greater risk of developing immune diseases such as asthma, allergies, type 1 diabetes, and celiac disease.

Author links open overlay panelClara E. Cho BSc a, a, b, & This review examines the relation between the mode of delivery and development of the immune system in the offspring. Recent epidemiological studies provide evidence that elective cesarean section (CS) is associated with aberrant short-term immune respons. (2012, August 10). Cesarean section and development of the immune system in the offspring. American Journal of Obstetrics and Gynecology. https://www.sciencedirect.com/science/article/abs/pii/S0002937812008575

剖腹產會中斷新生兒與母體陰道微生物群的接觸。 剖腹產分娩的嬰兒獲得的微生物群與陰道分娩的嬰兒不同，剖腹產分娩會增加免疫和代謝疾病的風險。

Exposure of newborns to the maternal vaginal microbiota is interrupted with cesarean birthing. Babies delivered by cesarean section acquire a microbiota that differs from that of vaginally delivered infants, and cesarean section delivery has been associated with increased risk for immune and metabolic disorders.

Dominguez-Bello, M. G., De Jesus-Laboy, K. M., Shen, N., Cox, L. M., Amir, A., Gonzalez, A., Bokulich, N. A., Song, S. J., Hoashi, M., Rivera-Vinas, J. I., Mendez, K., Knight, R., & Clemente, J. C. (2016, February 1). Partial restoration of the microbiota of cesarean-born infants via vaginal microbial transfer. Nature News. https://www.nature.com/articles/nm.4039