Fatty liver

Under some conditions, lipids may accumulate in the hepatocytes, resulting in the abnormal condition called fatty liver.
Smeltzer, S.C., & Bare, B.G. (2008). Brunner & Suddarth's Textbook of Medical-Surgical Nursing. Philadelphia, PA: LWW

The prevalence of non-alcoholic fatty liver disease (NAFLD) is highest in populations with pre-existing metabolic conditions such as obesity and type II diabetes.

Vernon, G., & Baranova, A. (30 May 2011). Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults. Wiley Online Library. Retrieved from

http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2036.2011.04724.x/full

The management of patients with NAFLD consists of treating liver disease as well as the associated metabolic co-morbidities such as obesity, hyperlipidemia, insulin resistance and T2DM. As patients with NAFLD without steatohepatitis have excellent prognosis from a liver standpoint, treatments aimed at improving liver disease should be limited to those with non-alcoholic steatohepatitis (NASH)...

The best evidence for weight loss as a means to improve liver histology in NASH comes from a trial that randomized 31 obese persons with NASH to intensive lifestyle changes (diet, behavior modification and 200 minutes a week of moderate physical activity for 48 weeks) versus structured basic education alone.

Chalasani, N. & Younossi, Z. (29 May 2012).The diagnosis and management of non-alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association. Wiley Online Library. Retrieved from

http://onlinelibrary.wiley.com/doi/10.1002/hep.25762/full

https://www.niddk.nih.gov/health-information/liver-disease/nafld-nash